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A histochemical study was performed in order to observe the changes of fallopian tubes during pregnancy. Forty-six cases of normal fallopian tubes were obtained at minilaparotomy for tubal sterilization during pregnancy and cesarean section. Two pieces of the tube, one from the isthmic and the other from the ampullar portion, were used in this study in order to study the differences between them. The results obtained were summarized as follows: 1. The average age and parity of these sterilization cases were 34.3 years and 3.3 respectively. 2. Fat was noted mildly in the cytoplasm of tubal epithelium, but was not present in the stroma and muscle. 3. Glycogen was seen moderately, as granules in the perinuclear portion of the tubal epithelium, but midly in the stroma and muscle. 4. Diastase resistant periodic acid Schiff reactive material markedly scattered over the basement membrane, stroma and muscle tissue. But its amount in the apical parts of the secretory cells in the tubal epithelium was only scanty. 5. Mucin content in the secretory cells of the tubal epithelium was slight in amount, but it was not noted in any other cells of the salpingeal tissue. 6. Alkaline phosphatase activity was identified along the surface of the secretory cells of tubal epithelium in mild degree, but moderately in the capillary and endothelium of the arteriole. 7. Acid phosphatase activity was observed moderately in the whole cytoplasm of the tubal epithelial cells with diffuse and granule forms. But its activity was not identified in any other sites of the tube. 8. Beta-glucuronidase activity was moderately present in the tubal epithelium, but it was mild in the stroma, muscle and blood vessel endothelium. 9. Esterase activity observed only slightly in the apical parts of the tubal epithelium and stroma, and it was not noted in any other sites of the tubal tissue. 10. Any differences in the contents of the above materials and enzymes were not identified between the isthmus and ampulla, and between the early and term
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